Kdo 2 ‐lipid A: structural diversity and impact on immunopharmacology
نویسندگان
چکیده
منابع مشابه
Kdo2-lipid A: structural diversity and impact on immunopharmacology
3-deoxy-d-manno-octulosonic acid-lipid A (Kdo2 -lipid A) is the essential component of lipopolysaccharide in most Gram-negative bacteria and the minimal structural component to sustain bacterial viability. It serves as the active component of lipopolysaccharide to stimulate potent host immune responses through the complex of Toll-like-receptor 4 (TLR4) and myeloid differentiation protein 2. The...
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ژورنال
عنوان ژورنال: Biological Reviews
سال: 2014
ISSN: 1464-7931,1469-185X
DOI: 10.1111/brv.12114